Afatinib
CAS 439081-18-2
In Stock
Afatinib
Cat. No. ANT-AFT-000CAS 439081-18-2In Stock
Technical Data
Cat. No.ANT-AFT-000
CAS439081-18-2
Mol. FormulaC24H25ClFN5O3
Mol. Weight485.94 g/mol
IUPAC(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
SMILESCN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4
InChIInChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1
InChI KeyULXXDDBFHOBEHA-CWDCEQMOSA-N
Purity99%
Description
Overview
Afatinib is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity. Afatinib is a tyrosine kinase receptor inhibitor that is used in the therapy of selected forms of metastatic non-small cell lung cancer
Anant Labs manufacture and furnish high quality Afatinib impurities for global markets. Our Afatinib EP Impurities are used by API manufacturers and fully integrated pharmaceutical companies worldwide.
Synonyms
(S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamideAfatinib850140-72-6BIBW2992TomtovokBIBW 2992BIBW-2992afatinibumNSC-75069141UD74L59M
