Desloratadine is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms
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Sinônimos
Desloratadine100643-71-8ClarinexDescarboethoxyloratadineAeriusDesloratidineNeoclaritynAzomyrSch-34117DenosinAllexOpulisSch 341178-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridineDesloratadine ActavisDasseltaDesloratadine teva8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-DesloratadinaDTXSID1044196NSC-759824FVF865388R8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridineDESLORATADINE RATIOPHARMDTXCID9024196CHEBI:2913428-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene5H-Benzo(5,6)cyclohepta(1,2-b)pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-DESLORATADINE TEVA (AUTHORIZED: RHINITIS, URTICARIA)DESLORATADINE ACTAVIS (AUTHORIZED: RHINITIS, URTICARIA)DESLORATADINE RATIOPHARM (AUTHORIZED: RHINITIS, URTICARIA)desloratadinumMidetorin8-Chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridine8-chloro-11-piperidin-4-ylidene-5,6-dihydrobenzo(1,2)cyclohepta(2,4-b)pyridine8-chloro-11-piperidin-4-ylidene-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridine13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo(9.4.0.0^(3,8))pentadeca-1(11),3,5,7,12,14-hexaene13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaene13-chloro-2-piperidin-4-ylidene-4-azatricyclo(9.4.0.03,8)pentadeca-1(11),3(8),4,6,12,14-hexaeneRefChem:57884R06AX2713-chloro-2-(piperidin-4-ylidene)-4-azatricyclo(9.4.0.03,8)pentadeca-1(11),3(8),4,6,12,14-hexaeneMFCD00871949DescarboethoxyoratidineCHEMBL11728-chloro-6,11-dihydro-11-(4-piperdinylidene)-5h-benzo[5,6]cyclohepta[1,2-b]pyridineMLS000559042NSC675447NCGC00159325-02SMR000149358Desloratadine [USAN]Clarinex RediTabsDesalexClarinex (TN)8-Chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (Descarboethoxyloratadine; Desloratadine)CAS-100643-71-8SR-01000668962Loratadine EP Impurity DUNII-FVF865388RNeoClarityn;Claramax;Clarinex;Desloratadine [USAN:INN:BAN]Desloratadine-d74-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta(1,2-b]pyridin-11-ylidene)-piperidine4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine4-{8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene}-piperidine4-{8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene}piperidineDesloratadine CRSLoratadine metabolite8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDINYLIDENE)-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE-D5MK-4117CPD000149358Desloratadine (Standard)Opera_ID_1891DESLORATADINE [MI]DESLORATADINE [INN]DESLORATADINE [JAN]SCHEMBL4425DESLORATADINE [VANDF]MLS000759406MLS001201801MLS001424247DESLORATADINE [MART.]DESLORATADINE [USP-RS]DESLORATADINE [WHO-DD]Desloratadine (JAN/USP/INN)GTPL7157orb1305363orb3139529DESLORATADINE [EMA EPAR]SCHEMBL29371361SCHEMBL29390260HY-B0539RDesloratadine - Bio-X trade markGLXC-03578HMS2052H05HMS2090C06HMS2093F19HMS3394H05HMS3652O15HMS3715J15HMS3885C18HMS5082N15Pharmakon1600-01505393DESLORATADINE [ORANGE BOOK]ALBB-027276ARD10141HY-B0539MSK10141VQB71934VWC02482DESLORATADINE [EP MONOGRAPH]Tox21_111574BBL010777BDBM50073179DESLORATADINE [USP MONOGRAPH]EBC-06071NSC759824s4012STK586537AKOS000280921Tox21_111574_1AC-1279CCG-101162DB00967KS-1048NC00412NSC 759824NSC-675447SB175038-chloro-6,11-dihydro-11-(4-piperdinylidene)- 5H-benzo[5,6]cyclohepta[1,2-b]pyridineDesloratadine for system suitability CRSDesloratadine; Loratadine EP Impurity DCLARINEX-D COMPONENT DESLORATADINEDesloratadine, powder, >=98% (HPLC)NCGC00159325-03NCGC00159325-04NCGC00159325-05BD164361SY053082SBI-0206828.P001LORATADINE IMPURITY D [EP IMPURITY]D1774D3787NS00008826SW197792-3D03693H11943AB00456701-11AB00456701-13AB00456701_14AB00456701_15EN300-1589139F375848L001025Q418060RUPATADINE FUMARATE IMPURITY B [EP IMPURITY]SR-01000668962-4SR-01000668962-5SR-01000668962-8BRD-K82357231-001-13-4BRD-K82357231-001-17-5BRD-K82357231-001-18-3BRD-K82357231-001-19-1Z2235801903Desloratadine, European Pharmacopoeia (EP) Reference StandardDesloratadine, United States Pharmacopeia (USP) Reference Standard4-(8-chloro-5,6-dihydro-11 H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine4-(8-chloro-5,6-dihydro-11H-benzo-[5,6]cyclohepta(1,2-b]pyridin-11-ylidene)-piperidine4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta [1,2-b]pyridin-11-ylidene) piperidine4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene) piperidine8-chloro-11-(4-piperidinylidene)-6,11-dihydro-5H- benzo[4,5]cyclohepta[2,1-b]pyridine8-chloro-11-(4-piperidyliden)-6,11-dihydro-5H-benzo[5,6]cyclohepta [1,2-b]pyridine8-chloro-11-(4-piperidyliden)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine8-chloro-11-(4-piperidylidene)-6,11-dihydro-5h-benzo[5.6]cyclohepta[1,2-b]pyridine8-Chloro-5,6-dihydro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine)8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine8-chloro-6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridineDesloratadine for system suitability, European Pharmacopoeia (EP) Reference StandardDesloratidine, Pharmaceutical Secondary Standard; Certified Reference Material13-chloro-2-(4-piperidylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0,3,8]pentadeca-1(11),3(8),4,6,12,14-hexaene13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene8-CHLORO-11-(4-PIPERIDYLIDENE)-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDINE
