Avanafil
CAS 330784-47-9
Em Estoque
Avanafil
Cat. No. STUB-API-AVANAFILCAS 330784-47-9Em Estoque
Dados Técnicos
Cat. No.STUB-API-AVANAFIL
CAS330784-47-9
Fórmula Mol.C23H26ClN7O3
Peso Mol.483.96 g/mol
IUPAC4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
SMILESCOC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCC[C@H]4CO)Cl
InChIInChI=1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1
Chave InChIWEAJZXNPAWBCOA-INIZCTEOSA-N
Pureza—
Descrição
Visão geral
Avanafil is used to treat erectile dysfunction (ED).Avanafil inhibits phosphodiesterase-5, preventing the degradation of cGMP.[11][12] The increased levels of cGMP causes vasodilation, resulting in an increased blood flow in the penis.[12] Avanafil's mechanism of action takes places once nitric oxide is released, in association with sexual stimulation
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Sinônimos
Avanafil330784-47-9STENDRASpedraTA-1790TA 1790AvanafiloDR5S136IVOCHEBI:66876(S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide
