Afatinib

CAS 439081-18-2

Visão geral

Afatinib is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity. Afatinib is a tyrosine kinase receptor inhibitor that is used in the therapy of selected forms of metastatic non-small cell lung cancer

A Anant Labs fabrica e fornece impurezas de Afatinib de alta qualidade para o mercado global. Nossas impurezas EP de Afatinib são utilizadas por fabricantes de APIs e empresas farmacêuticas totalmente integradas em todo o mundo.

Em Estoque

Afatinib

Cat. No. ANT-AFT-000CAS 439081-18-2Em Estoque

Dados Técnicos

Cat. No.ANT-AFT-000

CAS439081-18-2

Fórmula Mol.C₂₄H₂₅ClFN₅O₃

Peso Mol.485.94 g/mol

IUPAC(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide

SMILESCN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4

InChIInChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1

Chave InChIULXXDDBFHOBEHA-CWDCEQMOSA-N

Pureza99%

Sinônimos

(S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamideAfatinib850140-72-6BIBW2992TomtovokBIBW 2992BIBW-2992afatinibumNSC-75069141UD74L59M